The church of San Francesco was accomplished in 1270. Despite several adjustments that followed one another in the centuries, it maintains its Medieval structure. The church consists of one single nave with three spans covered by ogival crosses. The area of the presbytery, raised as against the nave, consists of various rooms, which is quite unusual. The façade has an outstanding pointed portal and an elegant rose-window. The cloister is the only remaining part of the convent, founded at the beginning of the XIII century and destroyed by the devastating earthquake occurred in 1915.
The sanctuary, a place of pilgrimage for centuries, is located in the surroundings of Tagliacozzo. Already existed in the 16th century, the icon of our Lady of the Orient 13th that it says was moved here from Ravenna where he arrived after escaping iconoclastic persecution of Byzantium.
In the Oriental Museum which houses an interesting collection of ex votos, Byzantine icons, vestments and coins coming from the Middle East.